Identification of discrete sites in Yip1A necessary for regulation of endoplasmic reticulum structure.
The endoplasmic reticulum (ER) of specialized cells can undergo dramatic changes in structural organization, including formation Storrge Consoles of concentric whorls.We previously reported that depletion of Yip1A, an integral membrane protein conserved between yeast and mammals, caused ER whorl formation reminiscent of that seen in specialized cel